The effect of nicotine on the brain

We all know that nicotine e-liquid contains nicotine, which is also one of the important factors that cause smoking. When we use high concentrations of nicotine base e-liquid, we can even feel the feeling of nicotine that hits the brain, showing that nicotine actually affects the brain.

There is now a surprising news that it is positive to discover the effects of nicotine on brain activity.

Don't expect experts to start distributing cigarettes for brain health research, but the discovery does trigger a new national study of how non-addictive nicotine patches stimulate the brain.

Dr. Jacobo Minzter, Chief Research and Innovation Officer at Roper St. Francis, said: "We know it may affect memory and attention."

Currently, 29 national research centers, including Roper St. Francis, are seeking research participants to improve memory through nicotine administration or MIND studies. The project will undergo a two-year review that will reveal the positive effects that nicotine may have on memory impairment.

In a 2004 study, researchers thought that people with ADHD and schizophrenia often smoke heavily because it may alleviate some of their symptoms.

Because it is difficult to maintain attention or concentration is one of these symptoms, the researchers found that nicotine activates specific areas of the brain that require concentration in specific tasks.

Through the MIND study, researchers hope to learn more about the brain's use of nicotine, especially in the case of mild cognitive impairment or mild cognitive impairment (MCI).

"Our goal is to fully understand how nicotine patches improve the memory of patients with mild cognitive impairment (MCI)," Minzter said.

Participants must: Age 55 or older. Non-smokers, no obvious neurological diseases. Mild cognitive dysfunction (MCI) usually manifests as an early sign of Alzheimer's disease. Not all people with mild cognitive impairment (MCI) progress in Alzheimer's, but mild cognitive impairment (MCI) does lead to mild memory loss, language and decision making difficulties.

Mintzer explained that although aging usually leads to memory loss, the memory loss of mild cognitive impairment (MCI) is more intense. If no expert diagnoses correctly, it may be ignored.

According to the National Alzheimer's Association, about 15% to 20% of people over the age of 65 have mild cognitive impairment (MCI).

“This is something that they may not notice in their daily lives,” Minzter said.

The MIND study participants will first be extensively examined to determine if they have mild cognitive impairment (MCI). Once determined, participants will receive a daily nicotine or placebo patch for the next two years, taking it every three months for a total of 12 visits.

At the end of the study, Minzter expressed the hope that they would better understand how nicotine works and develop FDA-approved treatments for mild cognitive impairment (MCI) symptoms. Ideally, researchers also want to know if nicotine treatment can effectively delay the progression of mild cognitive impairment (MCI) to Alzheimer's and dementia.

For those with mild cognitive impairment (MCI), nicotine may be an effective treatment and may delay the progression of downhill progression in Alzheimer's or other forms of dementia. Cindy Alewine, CEO of the Alzheimer's Association in South Carolina, explained that this is an important reason people are involved in these types of research.

She said that one of the most important obstacles to any type of research with Alzheimer's disease is funding. The second obstacle is finding enough participants.

Then, if anyone with mild cognitive dysfunction later, we give them a high concentration of nicotine base e-liquid, will also have a good therapeutic effect? It is not that vapes have the function of curing diseases. We expect the results of the research to come out as soon as possible.