Who is synthesizing nicotine?

Next Generation Labs, LLC (San Diego, California, USA) is one of the few companies producing smoke-free nicotine (TFN). Under Ron Tully's leadership, the company is now working on the synthesis of nicotine "for mass production of pure (R, S) -nicotine, and steam treatment for tobacco cessation and / or recreational use."

Next-generation labs also label their synthetic nicotine because pharmaceutical companies are interested in the main product, nicotine, but also their analogs (for the treatment of Parkinson, Alzheimer, attention deficit hyperactivity disorder (ADHD) ) Or brain disorders such as epilepsy).

In an interview with vape Radio, Ron Tully explained what TFN (synthetic derived nicotine) is and how it is considered a great alternative to traditional nicotine products. Its price is discounted. At first it was $ 125,000 per liter, but now it has dropped to $ 5,000 per liter, and it competes with natural S-Nicotine (about $ 4,000 per liter, Sigma-Aldrich). According to veterans of the tobacco industry, it has the advantages of odorless, tasteless and high purity compared with natural extracts.

Only a few liquid e liquid brands, such as Coastline, CRFT Labs and KVASS (14 in total) use smokeless nicotine, and most markets use tobacco-derived nicotine. According to the founder, tobacco extract still has a plant odor, which has caused e-liquid manufacturers to have to cover off odors with sweeteners and offensive flavors.

According to the Next Generation Lab, TFN nicotine has three selling points:

1. Lack of many impurities contained in tobacco-derived nicotine,

2, almost colorless and tasteless,

3. Significantly improve e-liquid flavors while providing the same biological effects as tobacco-derived nicotine.

The latest technology for synthesizing nicotine claims that kerosene is often used as a solvent for nicotine extraction from tobacco, but purification cannot achieve complete cleansing of the extract. It writes that "many of these pollutants are harmful to the human system, many have been proven to be carcinogenic, and have increased the addiction of 'nicotine'." The synthetic manufacturing scheme involves a multi-step process involving ethyl nicotinate as the backbone A synthetic method in which various atoms are added by a specific reaction using different compounds having low toxicity or toxicity.

Whether the FDA has jurisdiction over tobacco-free or synthetic nicotine products is unclear. The FDA responded that it would study these products on a case-by-case basis.

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